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      Glioma-derived extracellular vesicles selectively suppress immune responses.

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          Abstract

          Glioma-related immunosuppression is well documented; however, the mechanisms of suppression are not fully understood. Here we explore a role for glioma extracellular vesicles (EVs) as a means of immune modulation.

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          Author and article information

          Journal
          Neuro-oncology
          Neuro-oncology
          1523-5866
          1522-8517
          Apr 2016
          : 18
          : 4
          Affiliations
          [1 ] Dept of Neurosurgery, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado (J.E.H, T.A.H, D.G., M.W.G); Skaggs School of Pharmacy, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado (J.S.R, T.J.A).
          Article
          nov170
          10.1093/neuonc/nov170
          26385614
          2dcae50a-a67c-4ef9-b81e-e09c9883a96f
          © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
          History

          T cells,exosomes/extracellular vesicles,glioma,immune suppression,immunology

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