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      Risky sexual networks and concentrated HIV epidemics among men who have sex with men in Wenzhou, China: a respondent-driven sampling study.

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          Abstract

          The high and continually increasing prevalence of human immunodeficiency virus (HIV) and other sexually transmitted diseases among men who have sex with men (MSM) in China underscores the critical importance of examining the exact sexual networks that result in HIV transmission, as well as HIV infection, using powerful sampling methods, such as respondent-driven sampling (RDS), to improve the sexual health of this population.

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          An empirical comparison of respondent-driven sampling, time location sampling, and snowball sampling for behavioral surveillance in men who have sex with men, Fortaleza, Brazil.

          Halley Pontes, Guilherme Werneck, Keith Sabin … (2008)
          Obtaining samples of populations at risk for HIV challenges surveillance, prevention planning, and evaluation. Methods used include snowball sampling, time location sampling (TLS), and respondent-driven sampling (RDS). Few studies have made side-by-side comparisons to assess their relative advantages. We compared snowball, TLS, and RDS surveys of men who have sex with men (MSM) in Forteleza, Brazil, with a focus on the socio-economic status (SES) and risk behaviors of the samples to each other, to known AIDS cases and to the general population. RDS produced a sample with wider inclusion of lower SES than snowball sampling or TLS-a finding of health significance given the majority of AIDS cases reported among MSM in the state were low SES. RDS also achieved the sample size faster and at lower cost. For reasons of inclusion and cost-efficiency, RDS is the sampling methodology of choice for HIV surveillance of MSM in Fortaleza.
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            Social networking technologies as an emerging tool for HIV prevention: a cluster randomized trial.

            Greg Szekeres, William Cumberland, Devan Jaganath … (2013)
            Social networking technologies are an emerging tool for HIV prevention. To determine whether social networking communities can increase HIV testing among African American and Latino men who have sex with men (MSM). Randomized, controlled trial with concealed allocation. (ClinicalTrials.gov: NCT01701206). Online. 112 MSM based in Los Angeles, more than 85% of whom were African American or Latino. Sixteen peer leaders were randomly assigned to deliver information about HIV or general health to participants via Facebook groups over 12 weeks. After participants accepted a request to join the group, participation was voluntary. Group participation and engagement were monitored. Participants could request a free, home-based HIV testing kit and completed questionnaires at baseline and 12-week follow-up. Participant acceptance of and engagement in the intervention and social network participation, rates of home-based HIV testing, and sexual risk behaviors. Almost 95% of intervention participants and 73% of control participants voluntarily communicated using the social platform. Twenty-five of 57 intervention participants (44%) requested home-based HIV testing kits compared with 11 of 55 control participants (20%) (difference, 24 percentage points [95% CI, 8 to 41 percentage points]). Nine of the 25 intervention participants (36%) who requested the test took it and mailed it back compared with 2 of the 11 control participants (18%) who requested the test. Retention at study follow-up was more than 93%. Only 2 Facebook communities were included for each group. Social networking communities are acceptable and effective tools to increase home-based HIV testing among at-risk populations. National Institute of Mental Health.
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              Syphilis and human immunodeficiency virus (HIV)-1 coinfection: influence on CD4 T-cell count, HIV-1 viral load, and treatment response.

              Jan Gerstoft, Ulrik Mathiesen, Kristian Kofoed … (2006)
              To assess the effect of human immunodeficiency virus (HIV)-1 and syphilis coinfection on HIV-ribonucleic acid (RNA) viral load, CD4 cell count, and the response in rapid plasmin reagin (RPR) to treatment of the syphilis infection. Cases of syphilis diagnosed during 1 year in HIV-infected patients in Copenhagen were included. HIV-RNA, CD4 cell counts, and RPR-serology were measured before, during, and after syphilis. Forty-one patients were included. CD4 cell count decreased significantly during infection in patients with primary and secondary stages of syphilis (mean 106 cells/mm, P = 0.03). Treatment of syphilis was associated with an increase in the CD4 cell count and a decrease in HIV-RNA in the overall group (mean 66 cells/mm and -0.261 RNA log10 copies/ml, P = 0.02 and 0.04). The serological response rates for 15 patients treated with penicillin and 25 treated with doxycycline were the same. Syphilis was associated with a decrease in CD4 cell counts and an increase in HIV-RNA levels that both improved after treatment of syphilis.
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                Author and article information

                Journal
                Journal ID (iso-abbrev): BMC Public Health
                Title: BMC public health
                Publisher: Springer Science and Business Media LLC
                ISSN (Electronic): 1471-2458
                ISSN (Print): 1471-2458
                Publication date (Electronic): Dec 16 2015
                Volume: 15
                Affiliations
                [1 ] Department of HIV/STD Control, Center for Disease Control and Prevention of Zhejiang Province, No.3399, Binsheng Road, Hangzhou, 310051, People's Republic of China. qiaoqinma@aliyun.com.
                [2 ] Center for Disease Control and Prevention of Wenzhou Municipality, Wenzhou, 3250051, People's Republic of China. zsdcdc@126.coml.
                [3 ] Department of HIV/STD Control, Center for Disease Control and Prevention of Zhejiang Province, No.3399, Binsheng Road, Hangzhou, 310051, People's Republic of China. Shchxia@cdc.zj.cn.
                [4 ] Department of HIV/STD Control, Center for Disease Control and Prevention of Zhejiang Province, No.3399, Binsheng Road, Hangzhou, 310051, People's Republic of China. xhpan@cdc.zj.cn.
                [5 ] Center for Disease Control and Prevention of Wenzhou Municipality, Wenzhou, 3250051, People's Republic of China. wdychn@163.com.
                [6 ] Center for Disease Control and Prevention of Lucheng District, Wenzhou, 325001, People's Republic of China. 490051406@qq.com.
                [7 ] Department of HIV/STD Control, Center for Disease Control and Prevention of Zhejiang Province, No.3399, Binsheng Road, Hangzhou, 310051, People's Republic of China. huiwang@cdc.zj.cn.
                [8 ] Department of HIV/STD Control, Center for Disease Control and Prevention of Zhejiang Province, No.3399, Binsheng Road, Hangzhou, 310051, People's Republic of China. ttjiang@cdc.zj.cn.
                [9 ] Department of HIV/STD Control, Center for Disease Control and Prevention of Zhejiang Province, No.3399, Binsheng Road, Hangzhou, 310051, People's Republic of China. lhe@cdc.zj.cn.
                [10 ] Center for Disease Control and Prevention of Lucheng District, Wenzhou, 325001, People's Republic of China. 351515007@qq.com.
                [11 ] Nanjing Medical University School of Public Health, Nanjing, 211166, People's Republic of China. zhihangpeng@163.com.
                Article
                Publisher Item ID: 10.1186/s12889-015-2591-7
                DOI: 10.1186/s12889-015-2591-7
                PMC ID: 4682249
                PubMed ID: 26673429
                SO-VID: 2020c004-563a-478a-99f6-b58f803680da
                History

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