Uncovering the serine hydrolytic landscape of <i>Mycobacterium tuberculosis</i>

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

A new study utilizing a click-chemistry-enabled fluorophosphonate for activity-based identification of serine hydrolases, labeled a range of proteins including previously annotated hypotheticals. The application of this technology on actively replicating and non-replicating Mycobacterium tuberculosis gives us a glimpse of its serine hydrolytic landscape during different stages of metabolic activity.

Related collections

Author and article information

Journal

Journal ID (nlm-journal-id): 101676030

Journal ID (pubmed-jr-id): 44856

Journal ID (nlm-ta): Cell Chem Biol

Journal ID (iso-abbrev): Cell Chem Biol

Title: Cell chemical biology

ISSN (Print): 2451-9456

ISSN (Electronic): 2451-9448

Publication date Nihms-submitted: 22 December 2018

Publication date (Print): 18 February 2016

Publication date PMC-release: 29 January 2019

Volume: 23

Issue: 2

Pages: 209-211

Affiliations

Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD20892-3206, USA

Article

Accession ID: PMC6350241 Pmcid ID: PMC6350241 Pmc-uid ID: 6350241 Manuscript ID: nihpa1003071

DOI: 10.1016/j.chembiol.2016.02.002

PMC ID: 6350241

PubMed ID: 26971871

SO-VID: 166d3125-0059-4dcd-b0ac-48e1e92fad57

History

Comments

Comment on this article

scite_

Smart Citations

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.