Effects of high-protein diet on glycemic control, insulin resistance and blood pressure in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials.

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Abstract

Obesity is a well-known risk factor of type 2 diabetes mellitus (T2DM), and it is commonly accompanied by T2DM. It is estimated that almost two thirds of the population with T2DM is also affected by hypertension. Elevated arterial blood pressure would increase the risk for diabetes development. Recently some studies indicated that a high-protein diet was effective for weight loss, and therefore we hypothesized that a high-protein diet could help control blood glucose, mitigate insulin resistance (IR) and improve blood pressure by weight management in T2DM patients.

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Author and article information

Journal

Journal ID (iso-abbrev): Clin Nutr

Title: Clinical nutrition (Edinburgh, Scotland)

Publisher: Elsevier BV

ISSN (Electronic): 1532-1983

ISSN (Print): 0261-5614

Publication date (Electronic): June 2020

Volume: 39

Issue: 6

Affiliations

[1 ] Department of Clinical Nutrition, Dept. of Health Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

[2 ] Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

[3 ] Yale College, Yale University, New Haven, CT, USA.

[4 ] Institute for Emergency and Disaster Medicine, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Medical School of University of Electronic Science and Technology of China, Chengdu, China.

[5 ] Department of Clinical Nutrition, Dept. of Health Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address: txchenwei@sina.com.

[6 ] School of Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Article

Publisher Item ID: S0261-5614(19)33020-1

DOI: 10.1016/j.clnu.2019.08.008

PubMed ID: 31466731

SO-VID: dc4dd75c-6641-4c69-a2b1-e265c191562e

History

Keywords: Insulin resistance,Meta-analysis,Type 2 diabetes mellitus,Blood pressure,Glycemic control,High-protein diet

Data availability:

Keywords: Insulin resistance, Meta-analysis, Type 2 diabetes mellitus, Blood pressure, Glycemic control, High-protein diet

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