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      Dynamics of antimicrobial resistance of Streptococcus pneumoniae following PCV10 introduction in Brazil: Nationwide surveillance from 2007 to 2019.

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          Abstract

          Brazil introduced 10-valent pneumococcal conjugate vaccine (PCV10) into its immunization program in 2010. We assessed antimicrobial susceptibility of Streptococcus pneumoniae (Spn) obtained from a national surveillance system for invasive pneumococcal diseases (IPD) before/after PCV10 introduction.

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          Author and article information

          Journal
          Vaccine
          Vaccine
          Elsevier BV
          1873-2518
          0264-410X
          May 27 2021
          : 39
          : 23
          Affiliations
          [1 ] National Laboratory for Meningitis and Pneumococcal Infection, Center of Bacteriology, Adolfo Lutz Institute, São Paulo, State of São Paulo, Brazil. Electronic address: maria.brandileone@ial.sp.gov.br.
          [2 ] National Laboratory for Meningitis and Pneumococcal Infection, Center of Bacteriology, Adolfo Lutz Institute, São Paulo, State of São Paulo, Brazil. Electronic address: samanta.almeida@ial.sp.gov.br.
          [3 ] National Laboratory for Meningitis and Pneumococcal Infection, Center of Bacteriology, Adolfo Lutz Institute, São Paulo, State of São Paulo, Brazil. Electronic address: sergio.bokermann@ial.sp.gov.br.
          [4 ] Faculty of Nursing, Federal University of Goiás, Goiânia, State of Goiás, Brazil. Electronic address: minamisava@gmail.com.
          [5 ] Santa Casa Medical School of São Paulo, State of São Paulo, Brazil. Electronic address: berezin@terra.com.br.
          [6 ] Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: lharriso@edc.pitt.edu.
          [7 ] Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, State of Goiás, Brazil. Electronic address: alssandrade@gmail.com.
          Article
          S0264-410X(21)00254-1
          10.1016/j.vaccine.2021.02.063
          33707062
          b711cbbf-c06d-4fbc-a4cb-37d02ec1a3bf
          History

          Antimicrobial resistance,Invasive pneumococcal diseases,Multidrug resistance,PCV10,Pneumococcal conjugate vaccine,Pneumococcal serotypes,Streptococcus pneumoniae

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