Depression.

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Abstract

Major depression is a common illness that severely limits psychosocial functioning and diminishes quality of life. In 2008, WHO ranked major depression as the third cause of burden of disease worldwide and projected that the disease will rank first by 2030.1 In practice, its detection, diagnosis, and management often pose challenges for clinicians because of its various presentations, unpredictable course and prognosis, and variable response to treatment.

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Journal

Journal ID (iso-abbrev): Lancet

Title: Lancet (London, England)

Publisher: Elsevier BV

ISSN (Electronic): 1474-547X

ISSN (Print): 0140-6736

Publication date (Electronic): November 24 2018

Volume: 392

Issue: 10161

Affiliations

[1 ] Department of Academic Psychiatry, Sydney Medical School Northern, University of Sydney, Sydney, NSW, Australia; CADE Clinic, Royal North Shore Hospital, Sydney, NSW, Australia. Electronic address: gin.malhi@sydney.edu.au.

[2 ] Molecular Imaging and Neuropathology Division, Department of Psychiatry, Columbia University, New York, NY, USA.

Article

Publisher Item ID: S0140-6736(18)31948-2

DOI: 10.1016/S0140-6736(18)31948-2

PubMed ID: 30396512

SO-VID: 89ce8392-1d4e-4272-9b14-c361c7b80cbd

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