Lidocaine infusion has a 25% opioid-sparing effect on background pain after burns: A prospective, randomised, double-blind, controlled trial.

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Abstract

The pain of a burn mainly results from the inflammatory cascade that is induced by the injured tissue, and is classified as background, breakthrough, procedural and postoperative pain. High doses of opioids are usually needed to treat background pain, so its management includes a combination of types of analgesia to reduce the side effects. Lidocaine given intravenously has been shown in two small, uncontrolled studies to have an appreciable effect on pain after burns.

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Journal

Journal ID (iso-abbrev): Burns

Title: Burns : journal of the International Society for Burn Injuries

Publisher: Elsevier BV

ISSN (Electronic): 1879-1409

ISSN (Print): 0305-4179

Publication date (Electronic): March 2020

Volume: 46

Issue: 2

Affiliations

[1 ] The Department of Hand Surgery, Plastic Surgery and Burns, and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden; Plastic Surgery Unit, Surgery Department, Suez Canal University, Ismailia, Egypt. Electronic address: islam.abdelrahman@liu.se.

[2 ] The Department of Hand Surgery, Plastic Surgery and Burns, and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

[3 ] The Department of Hand Surgery, Plastic Surgery and Burns, and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden; Plastic Surgery Unit, Surgery Department, Suez Canal University, Ismailia, Egypt.

[4 ] The Department of Hand Surgery, Plastic Surgery and Burns, and Department of Clinical and Experimental Medicine, and Department of Anaesthesiology and Intensive Care, Linköping University, Linköping, Sweden.

Article

Publisher Item ID: S0305-4179(19)30183-4

DOI: 10.1016/j.burns.2019.08.010

PubMed ID: 31493952

SO-VID: 9e34adf4-b715-4de0-b863-5553654d9ddd

History

Keywords: Opioid sparing effect,Randomized controlled trial,Lidocaine infusion,Burns,Background pain

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Keywords: Opioid sparing effect, Randomized controlled trial, Lidocaine infusion, Burns, Background pain

Lidocaine infusion has a 25% opioid-sparing effect on background pain after burns: A prospective, randomised, double-blind, controlled trial.

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