Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies.

Aziz, Nur Khairunnisa Abdul; Kim, Mi-Yeon; Cho, Jae Youl

doi:10.1016/j.jep.2018.05.019

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Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies.

Author(s): Nur Aziz ¹ , Mi-Yeon Kim ² , Jae Youl Cho ³

Publication date (Electronic): Oct 28 2018

Journal: Journal of ethnopharmacology

Publisher: Elsevier BV

Keywords: Flavonoid, Inflammatory diseases, Inflammatory signaling, Luteolin, Luteolin (PubChem CID: 5280445), Luteolin-5-O-glucoside (PubChem CID: 44258061), Luteolin-6-C-glucoside (PubChem CID: 49852298), Luteolin-7-O-glucoside (PubChem CID: 5280637), Luteolin-8-C-glucoside (PubChem CID: 5281675)

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Abstract

Luteolin (3', 4', 5,7-tetrahydroxyflavone) has been identified as commonly present in plants. Plants with a high luteolin content have been used ethnopharmacologically to treat inflammation-related symptoms. Both isolated luteolin and extracts from luteolin-rich plants have been studied using various models and exhibited anti-inflammatory activity.

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Author and article information

Journal

Journal ID (iso-abbrev): J Ethnopharmacol

Title: Journal of ethnopharmacology

Publisher: Elsevier BV

ISSN (Electronic): 1872-7573

ISSN (Print): 0378-8741

Publication date (Electronic): Oct 28 2018

Volume: 225

Affiliations

[1 ] Department of Genetic Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.

[2 ] School of Systems Biomedical Science, Soongsil University, Seoul 06978, Republic of Korea. Electronic address: kimmy@ssu.ac.kr.

[3 ] Department of Genetic Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address: jaecho@skku.edu.

Article

Publisher Item ID: S0378-8741(17)33457-8

DOI: 10.1016/j.jep.2018.05.019

PubMed ID: 29801717

SO-VID: 0854e816-7d0f-484a-a3bf-d33d912dc281

History

Keywords: Luteolin,Luteolin-8-C-glucoside (PubChem CID: 5281675),Luteolin-7-O-glucoside (PubChem CID: 5280637),Luteolin-6-C-glucoside (PubChem CID: 49852298),Luteolin-5-O-glucoside (PubChem CID: 44258061),Luteolin (PubChem CID: 5280445),Inflammatory signaling,Inflammatory diseases,Flavonoid

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Keywords: Luteolin, Luteolin-8-C-glucoside (PubChem CID: 5281675), Luteolin-7-O-glucoside (PubChem CID: 5280637), Luteolin-6-C-glucoside (PubChem CID: 49852298), Luteolin-5-O-glucoside (PubChem CID: 44258061), Luteolin (PubChem CID: 5280445), Inflammatory signaling, Inflammatory diseases, Flavonoid

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