Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia.

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Abstract

The life expectancy of the population is increasing worldwide due to improvements in the prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 diabetes mellitus (T2DM) in the elderly. Sarcopenia and frailty are also frequently present in aging. These three entities share common mechanisms such as insulin resistance, chronic inflammation, and mitochondrial dysfunction. The coexistence of these situations worsens the prognosis of elderly patients. In this paper, we review the main measures for the prevention and management of sarcopenia and/or frailty in elderly patients with T2DM.

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Author and article information

Journal

Journal ID (iso-abbrev): Int J Environ Res Public Health

Title: International journal of environmental research and public health

Publisher: MDPI AG

ISSN (Electronic): 1660-4601

ISSN (Print): 1660-4601

Publication date (Electronic): Jul 16 2022

Volume: 19

Issue: 14

Affiliations

[1 ] Unidad de Gestión Clínica de Medicina Interna, Hospital Regional Universitario de Málaga, Universidad de Málaga (UMA), 29010 Málaga, Spain.

[2 ] Instituto de Investigación Biomédica de Málaga (IBIMA-Plataforma Bionand), 29590 Málaga, Spain.

[3 ] Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Article

Publisher Item ID: ijerph19148677

DOI: 10.3390/ijerph19148677

PMC ID: 9318510

PubMed ID: 35886528

SO-VID: 5e7872e4-ab5b-4953-bd6b-e5e43f12898d

History

Keywords: sarcopenia,type 2 diabetes mellitus,elderly,frailty

Data availability:

Keywords: sarcopenia, type 2 diabetes mellitus, elderly, frailty

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