A Retrospective Analysis of Outcome in Melanoma Differentiation-Associated Gene 5-Related Interstitial Lung Disease Treated with Tofacitinib or Tacrolimus.

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Abstract

The efficacy of tofacitinib (TOF) in the early diagnosis of melanoma differentiation-associated gene 5 (MDA5)-related interstitial lung disease (ILD) has been described. However, whether TOF exposure is associated with a reduced 1-year mortality rate remains undetermined.

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Author and article information

Journal

Journal ID (iso-abbrev): J Rheumatol

Title: The Journal of rheumatology

Publisher: The Journal of Rheumatology

ISSN: 0315-162X

ISSN (Print): 0315-162X

Publication date (Electronic): Dec 2022

Volume: 49

Issue: 12

Affiliations

[1 ] L. Fan, MMed, W. Lyu, MMed, H. Liu, MMed, H. Jiang, MMed, L. Chen, MMed, Y. Liu, MMed, Y. Zhuang, PhD, M. Huang, MMed, M. Cao, MMed, H. Cai, MMed, Y. Xiao, MMed, and J. Dai, PhD, Department of Pulmonary and Critical Care Medicine, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, Jiangsu, China.

[2 ] L. Fan, MMed, W. Lyu, MMed, H. Liu, MMed, H. Jiang, MMed, L. Chen, MMed, Y. Liu, MMed, Y. Zhuang, PhD, M. Huang, MMed, M. Cao, MMed, H. Cai, MMed, Y. Xiao, MMed, and J. Dai, PhD, Department of Pulmonary and Critical Care Medicine, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, Jiangsu, China. yonglong11a@163.com.

[3 ] L. Fan, MMed, W. Lyu, MMed, H. Liu, MMed, H. Jiang, MMed, L. Chen, MMed, Y. Liu, MMed, Y. Zhuang, PhD, M. Huang, MMed, M. Cao, MMed, H. Cai, MMed, Y. Xiao, MMed, and J. Dai, PhD, Department of Pulmonary and Critical Care Medicine, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, Jiangsu, China. daijinghong@nju.edu.cn.

Article

Publisher Item ID: jrheum.220367

DOI: 10.3899/jrheum.220367

PubMed ID: 35970525

SO-VID: c96d1302-4621-4f97-b797-8ef5bed8135a

History

Keywords: interstitial lung disease,tofacitinib,MDA5,survival

Data availability:

Keywords: interstitial lung disease, tofacitinib, MDA5, survival

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