A comparison of the gut microbiome between long-term users and non-users of proton pump inhibitors.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Proton pump inhibitor (PPI) use is associated with an increased risk of Clostridium difficile infection (CDI), though the mechanism is unclear. PPI induced alterations to the gut microbiome may facilitate the emergence of CDI, though the effects of PPIs on gut microbiota are not well characterised. [Correction added on 10 March 2016, after first online publication: microflora has been changed to microbiota throughout the article.]

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Aliment. Pharmacol. Ther.

Title: Alimentary pharmacology & therapeutics

ISSN (Electronic): 1365-2036

ISSN (Print): 0269-2813

Publication date (Electronic): May 2016

Volume: 43

Issue: 9

Affiliations

[1 ] School of Microbiology & APC Microbiome Institute, University College Cork, Cork, Ireland.

[2 ] Section of Gastroenterology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.

[3 ] Departments of Radiology and Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.

Article

DOI: 10.1111/apt.13568

PubMed ID: 26923470

SO-VID: e7db3c6c-c261-4337-8fc1-42cbd2882f2a

History

Data availability:

Comments

Comment on this article

scite_

Cited by 67

See all cited by