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      Quality of life and level of satisfaction with pharmacotherapeutic follow-up in a transgender health center in Brazil

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          Abstract

          Trans people face numerous barriers to access and permanence in health services, which makes it difficult, among other things, to know about their quality of life and satisfaction with health services related to these users. Thus, the objective was to describle the quality of life and satisfaction with pharmacotherapeutic follow-up in transgender people. A cross-sectional, descriptive, and quantitative study was conducted between January and September 2022 at a specialized outpatient clinic for transgender individuals. The following aspects were describle: sociodemographic and medication profiles; quality of Life, which was measured using the WHOQOL-BREF questionnaire; and levels of satisfaction with Pharmacotherapeutic Monitoring, assessed through the Pharmacy Services Satisfaction Questionnaire (QSSF). Descriptive analyses employed measures of central tendency, absolute and relative frequencies, while inferential analyses used the Student’s t test. A total of 101 transgender individuals participated in the study, with a mean age of 25 years, the majority being single (79.2%/80), having more than 11 years of education (47.5%/n = 48), and comprising 48.5% (n = 49) transgender women. Hormone use was reported by 59.4% (n = 60) of the participants, with 18.3% (n = 11) of self-medication. Testosterone cypionate was the most common hormone used by transgender men (84%), while cyproterone acetate and estradiol represented 60.4% of hormone use among transgender women. Additionally, 36 transgender individuals were taking other drugs (n = 60), mainly antidepressives (28%). The WHOQOL-BREF showed higher scores in the domains of self-rated Quality of Life, and physical, and psychological well-being among transgender women compared to transgender men, but without statistical differences. Income revealed a statistically significant association with psychological domains and overall quality of life. The results of the QSSF indicated that the overall mean and average scores per question were higher than 4, suggesting that 100% of the sample was satisfied with the provided service. No statistically significant differences were observed in the Quality of Life between transgender men and women, but income was associated with the psychological domain and overall Quality of Life. All participants reported satisfaction with the Pharmacotherapeutic Monitoring service; however, there is a need to expand service offerings, such as medication dispensing.

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          HIV prevalence, risk behaviors, health care use, and mental health status of transgender persons: implications for public health intervention.

          This study described HIV prevalence, risk behaviors, health care use, and mental health status of male-to-female and female-to-male transgender persons and determined factors associated with HIV. We recruited transgender persons through targeted sampling, respondent-driven sampling, and agency referrals; 392 male-to-female and 123 female-to-male transgender persons were interviewed and tested for HIV. HIV prevalence among male-to-female transgender persons was 35%. African American race (adjusted odds ratio [OR] = 5.81; 95% confidence interval [CI] = 2.82, 11.96), a history of injection drug use (OR = 2.69; 95% CI = 1.56, 4.62), multiple sex partners (adjusted OR = 2.64; 95% CI = 1.50, 4.62), and low education (adjusted OR = 2.08; 95% CI = 1.17, 3.68) were independently associated with HIV. Among female-to-male transgender persons, HIV prevalence (2%) and risk behaviors were much lower. Most male-to-female (78%) and female-to-male (83%) transgender persons had seen a medical provider in the past 6 months. Sixty-two percent of the male-to-female and 55% of the female-to-male transgender persons were depressed; 32% of each population had attempted suicide. High HIV prevalence suggests an urgent need for risk reduction interventions for male-to-female transgender persons. Recent contact with medical providers was observed, suggesting that medical providers could provide an important link to needed prevention, health, and social services.
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            Unveiling of HIV dynamics among transgender women: a respondent-driven sampling study in Rio de Janeiro, Brazil

            The burden of HIV in transgender women (transwomen) in Brazil remains unknown. We aimed to estimate HIV prevalence among transwomen in Rio de Janeiro and to identify predictors of newly diagnosed HIV infections.
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              Is hormonal therapy associated with better quality of life in transsexuals? A cross-sectional study.

              Although the impact of sex reassignment surgery on the self-reported outcomes of transsexuals has been largely described, the data available regarding the impact of hormone therapy on the daily lives of these individuals are scarce.
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                Author and article information

                Contributors
                gisellecbrito@academico.ufs.br
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                21 February 2024
                21 February 2024
                2024
                : 14
                : 4259
                Affiliations
                [1 ]Graduate Program in Pharmaceutical Sciences, Federal University of Sergipe, ( https://ror.org/028ka0n85) São Cristóvão, Sergipe Brazil
                [2 ]Multiprofessional Residency in Hospital Health Care, University Hospital of Lagarto, Lagarto, Sergipe Brazil
                [3 ]Graduate Program in Applied Health Sciences, Federal University of Sergipe, ( https://ror.org/028ka0n85) Governador Marcelo Déda Avenue, São José District, Lagarto, Sergipe 49400-000 Brazil
                [4 ]Department of Pharmacy, Federal University of Sergipe, ( https://ror.org/028ka0n85) São Cristóvão, Brazil
                [5 ]Department of Pharmacy, Federal University of Sergipe, ( https://ror.org/028ka0n85) Lagarto, Brazil
                Author information
                http://orcid.org/0000-0002-1303-2103
                http://orcid.org/0000-0002-7470-273X
                http://orcid.org/0000-0002-0593-3497
                http://orcid.org/0000-0003-3192-8285
                http://orcid.org/0000-0002-1827-0856
                http://orcid.org/0000-0002-3982-2138
                Article
                54737
                10.1038/s41598-024-54737-y
                10881476
                38383586
                dd27a86e-49b0-40ed-9f16-9face32a64d3
                © The Author(s) 2024

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 29 August 2023
                : 15 February 2024
                Categories
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                © Springer Nature Limited 2024

                Uncategorized
                transgender persons,health services,patient satisfaction,quality of life,outcomes research

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