Vanessa Sancho-Shimizu:
ORCID: https://orcid.org/0000-0002-3519-0727
Role: ConceptualizationRole: Writing - original draftRole: Writing - review & editing
Petter Brodin:
ORCID: https://orcid.org/0000-0002-8103-0046
Role: ConceptualizationRole: SupervisionRole: Writing - original draftRole: Writing
- review & editing
Aurélie Cobat:
ORCID: https://orcid.org/0000-0001-7209-6257
Role: Data curationRole: Writing - original draftRole: Writing - review & editing
Catherine M. Biggs:
ORCID: https://orcid.org/0000-0002-4363-2660
Role: InvestigationRole: VisualizationRole: Writing - original draftRole: Writing
- review & editing
Julie Toubiana:
ORCID: https://orcid.org/0000-0001-9561-669X
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
ValidationRole: VisualizationRole: Writing - original draftRole: Writing - review
& editing
Carrie L. Lucas:
ORCID: https://orcid.org/0000-0002-5754-0820
Role: ConceptualizationRole: VisualizationRole: Writing - review & editing
Sarah E. Henrickson:
ORCID: https://orcid.org/0000-0001-5569-4132
Role: Writing - original draftRole: Writing - review & editing
Alexandre Belot:
ORCID: https://orcid.org/0000-0003-4902-5332
Role: ConceptualizationRole: Writing - review & editing
Stuart G. Tangye:
ORCID: https://orcid.org/0000-0002-5360-5180
Role: Writing - original draftRole: Writing - review & editing
Joshua D. Milner:
ORCID: https://orcid.org/0000-0002-3913-3869
Role: Writing - original draftRole: Writing - review & editing
Michael Levin:
ORCID: https://orcid.org/0000-0003-2767-6919
Role: Writing - original draftRole: Writing - review & editing
Laurent Abel:
ORCID: https://orcid.org/0000-0001-7016-6493
Role: ConceptualizationRole: Writing - original draftRole: Writing - review & editing
Dusan Bogunovic:
ORCID: https://orcid.org/0000-0002-9277-3232
Role: ConceptualizationRole: Funding acquisitionRole: Writing - original draftRole:
Writing - review & editing
Jean-Laurent Casanova:
ORCID: https://orcid.org/0000-0002-7782-4169
Role: Funding acquisitionRole: SupervisionRole: Writing - review & editing
Shen-Ying Zhang:
ORCID: https://orcid.org/0000-0002-9449-3672
Role: ConceptualizationRole: Data curationRole: Funding acquisitionRole: Writing -
original draftRole: Writing - review & editing
Journal ID (nlm-ta): J Exp Med
Journal ID (iso-abbrev): J Exp Med
Journal ID (publisher-id): jem
Title:
The Journal of Experimental Medicine
Publisher:
Rockefeller University Press
ISSN
(Print):
0022-1007
ISSN
(Electronic):
1540-9538
Publication date Collection: 07
June
2021
Publication date
(Electronic):
27
April
2021
Publication date PMC-release: 27
April
2021
Volume: 218
Issue: 6
Electronic Location Identifier: e20210446
Affiliations
[1
]Department of Paediatric Infectious Diseases and Virology, Imperial College London,
London, UK
[2
]Centre for Paediatrics and Child Health, Faculty of Medicine, Imperial College London,
London, UK
[3
]Science for Life Laboratory, Department of Women’s and Children’s Health, Karolinska
Institutet, Stockholm, Sweden
[4
]St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch,
The Rockefeller University, New York, NY
[5
]Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National
de la Santé et de la Recherche Médicale, Necker Hospital for Sick Children, Paris,
France
[6
]University of Paris, Imagine Institute, Paris, France
[7
]Department of Pediatrics, University of British Columbia, Vancouver, Canada
[8
]British Columbia Children’s Hospital Research Institute, Vancouver, Canada
[9
]Department of General Pediatrics and Pediatric Infectious Diseases, Necker Hospital
for Sick Children, Assistance Publique - Hôpitaux de Paris, University of Paris, Paris,
France
[10
]Pasteur Institute, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France
[11
]Department of Immunobiology, Yale University School of Medicine, New Haven, CT
[12
]Division of Allergy Immunology, Children’s Hospital of Philadelphia, Philadelphia,
PA
[13
]Department of Microbiology, Perelman School of Medicine, University of Pennsylvania,
Philadelphia, PA
[14
]Centre International de Recherche en Infectiologie, University of Lyon, Institut National
de la Santé et de la Recherche Médicale, U1111, Université Claude Bernard, Lyon 1,
Le Centre National de la Recherche Scientifique, UMR5308, Lyon, France
[15
]National Reference Center for Rheumatic, Autoimmune and Systemic Diseases in Children
(RAISE), Pediatric Nephrology, Rheumatology, Dermatology Unit, Hôpital Femme Mère
Enfant, Hospices Civils de Lyon, Lyon, France
[16
]Garvan Institute of Medical Research, Darlinghurst, Australia
[17
]St. Vincent’s Clinical School, Faculty of Medicine, University of New South Wales
Sydney, Sydney, Australia
[18
]Department of Pediatrics, Columbia University Irving Medical Center, New York, NY
[19
]Center for Inborn Errors of Immunity, Precision Immunology Institute, Mindich Child
Health and Development Institute, Department of Microbiology, Department of Pediatrics,
Icahn School of Medicine at Mount Sinai, New York, NY
[20
]Howard Hughes Medical Institute, New York, NY
[21
]Multisystem Inflammatory Syndrome in Children, COVID Human Genetic Effort
Author notes
Disclosures: The authors declare no competing interests exist.
All authors contributed equally to this paper.
Members of MIS-C@CHGE are listed at the end of the PDF.
Author information
Article
Publisher ID:
jem.20210446
DOI: 10.1084/jem.20210446
PMC ID: 8080850
PubMed ID: 33904890
SO-VID: d924822e-64a8-47eb-a9ec-bd8b58f642fa
Copyright © © 2021 Sancho-Shimizu et al.
License:
This article is distributed under the terms of an Attribution–Noncommercial–Share
Alike–No Mirror Sites license for the first six months after the publication date
(see
http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share
Alike 4.0 International license, as described at
https://creativecommons.org/licenses/by-nc-sa/4.0/).
Funded by: Howard Hughes Medical Institute, DOI http://dx.doi.org/10.13039/100000011;
Funded by: Rockefeller University, DOI http://dx.doi.org/10.13039/100012007;
Funded by: St. Giles Foundation, DOI http://dx.doi.org/10.13039/100002350;
Funded by: National Institutes of Health, DOI http://dx.doi.org/10.13039/100000002;
Award ID: R01AI088364
Award ID: R01AI148963
Award ID: R01AI151029
Award ID: R01AI150300
Award ID: K08AI135091
Award ID: R21AI144315-02S1
Funded by: National Center for Advancing Translational Sciences, DOI http://dx.doi.org/10.13039/100006108;
Funded by: National Institutes of Health, DOI http://dx.doi.org/10.13039/100000002;
Award ID: UL1 TR001866
Funded by: Yale Center for Mendelian Genomics;
Funded by: GSP Coordinating Center;
Funded by: National Human Genome Research Institute, DOI http://dx.doi.org/10.13039/100000051;
Award ID: UM1HG006504
Award ID: U24HG008956
Funded by: Institut National de la Santé et de la Recherche Médicale, DOI http://dx.doi.org/10.13039/501100001677;
Funded by: Université de Paris;
Funded by: UK Research and Innovation Future Leader’s Fellowship;
Award ID: MR/S032304/1
Funded by: NIHR Imperial Biomedical Research Centre, DOI http://dx.doi.org/10.13039/501100013342;
Funded by: Imperial College Healthcare NHS Trust, DOI http://dx.doi.org/10.13039/501100000762;
Award ID: 70931
Funded by: Burroughs Wellcome Fund, DOI http://dx.doi.org/10.13039/100000861;
Funded by: Clinical Immunology Society;
Funded by: American Academy of Allergy Asthma and Immunology, DOI http://dx.doi.org/10.13039/100002567;
Funded by: Michael Smith Foundation for Health Research, DOI http://dx.doi.org/10.13039/501100000245;
Funded by: National Health and Medical Research Council, DOI http://dx.doi.org/10.13039/501100000925;
Funded by: University of New South Wales, DOI http://dx.doi.org/10.13039/501100001773;
Funded by: French National Research Agency, DOI http://dx.doi.org/10.13039/501100001665;
Award ID: ANR-10-IAHU-01
Award ID: ANR-20-CO11-0001
Award ID: ANR-10-LABX-62-IBEID
Funded by: French Foundation for Medical Research;
Award ID: EQU201903007798
Funded by: Square Foundation;
Funded by: Grandir - Fonds de solidarité pour l’enfance;
Funded by: Fondation du Souffle, DOI http://dx.doi.org/10.13039/100012019;
Funded by: SCOR Corporate Foundation for Science;