Interpretation of mitochondrial tRNA variants.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

To develop criteria to interpret mitochondrial transfer RNA (mt-tRNA) variants based on unique characteristics of mitochondrial genetics and conserved structural/functional properties of tRNA.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Genet Med

Title: Genetics in medicine : official journal of the American College of Medical Genetics

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1530-0366

ISSN (Print): 1098-3600

Publication date (Electronic): May 2020

Volume: 22

Issue: 5

Affiliations

[1 ] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. ljwong@bcm.edu.

[2 ] Baylor Genetics Laboratory, Houston, TX, USA. ljwong@bcm.edu.

[3 ] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

[4 ] Department of Endocrinology, Genetics and Metabolism, Children's Hospital of Soochow University, Suzhou, China.

[5 ] Children's Hospital of Philadelphia, Philadelphia, PA, USA.

[6 ] WuXi NextCODE, Cambridge, MA, USA.

[7 ] Baylor Genetics Laboratory, Houston, TX, USA.

[8 ] Global Laboratory Services/Diagnostics, Perkin Elmer, Waltham, MA, USA.

[9 ] Otogenetic Corporation, Atlanta, GA, USA.

[10 ] Department of Pathology and Laboratory Medicine, UKHealthCare, University of Kentucky, Lexington, KY, USA.

[11 ] AmCare Genomics Lab, Guangzhou, China.

Article

Publisher Item ID: 10.1038/s41436-019-0746-0

DOI: 10.1038/s41436-019-0746-0

PubMed ID: 31965079

SO-VID: cdaa51c6-1d7e-4837-936c-f75a63abc282

History

Keywords: MitoTIP,mt-tRNA variants interpretation,tRNA variants classification criteria

Data availability:

Keywords: MitoTIP, mt-tRNA variants interpretation, tRNA variants classification criteria

Interpretation of mitochondrial tRNA variants.

Read this article at

Abstract

Related collections

Electrospinning for biomedical applications

Author and article information

Journal

Affiliations

Article

History

Comments

Comment on this article

Similar content 269

Cited by 17