Low human parvovirus B19 (B19V) DNA prevalence in blood donors from Central-West Brazil.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Parvovirus B19 (B19V) transmission may occur through blood transfusion as a result of asymptomatic viral persistence in blood donors. Our study evaluated the prevalence and viral load of B19V in blood donors from Brasilia, Federal District, Central-West Brazil. B19V DNA detection and quantification were performed in 477 blood donors. The positive samples were also tested for anti-B19V IgG and haemoderivative recipients were investigated for adverse effects following transfusion. B19V DNA prevalence was 0.21 % (n=1/477). The positive B19V DNA sample was also anti-B19 IgG-positive (probably persistent infection). The viral load was low and no adverse effects following blood transfusion were registered in the recipients. This study demonstrated that the B19V DNA prevalence in blood donors from Central-West Brazil is low. Nevertheless, the mere presence of B19V DNA in blood donors strengthens the need for viral molecular screening, especially in haemoderivatives that that will go to susceptible recipients.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): J. Med. Microbiol.

Title: Journal of medical microbiology

Publisher: Microbiology Society

ISSN (Electronic): 1473-5644

ISSN (Print): 0022-2615

Publication date (Electronic): Apr 2019

Volume: 68

Issue: 4

Affiliations

[1 ] Blood Center of Ribeirão Preto, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

[2 ] Department of Internal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

[3 ] Faculty of Ceilândia, University of Brasilia, Federal District, Brazil.

[4 ] Center for Tropical Medicine, University of Brasilia, Federal District, Brazil.

[5 ] Blood Center of Brasilia, Federal District, Brazil.

[6 ] Department of Clinical, Toxicological and Bromatological Analyses, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Article

DOI: 10.1099/jmm.0.000957

PubMed ID: 30843782

SO-VID: c862ae7b-2b6a-41f3-8a63-ad5f69cb7780

History

Keywords: prevalence,viral load,blood donors,parvovirus B19

Data availability:

Keywords: prevalence, viral load, blood donors, parvovirus B19

Comments

Comment on this article

scite_

Cited by 4

See all cited by