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      Identification of Polyp from Colonoscopy Images by Deep Belief Network based Polyp Detector Integration Model

      , , , , ,
      EAI Endorsed Transactions on Pervasive Health and Technology
      European Alliance for Innovation n.o.

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          Abstract

          Cancer is a disease involving unusual cell growth likely to spread to other parts of the body. According to WHO 2020 report, colorectal malignancy is the globally accepted second leading cause of cancer related deaths. Colorectal malignancy arises when malignant cells often called polyp, grow inside the tissues of the colon or rectum of the large intestine. Colonoscopy, CT scan, Histopathological analysis are some manual approaches of malignancy detection that are time consuming and lead to diagnostic errors. Supervised CNN data model requires a large number of labeled training samples to learn parameters from images. In this study we propose an expert system that can detect the colorectal malignancy and identify the exact polyp area from complex images. In this approach an unsupervised Deep Belief Network (DBN) is applied for effective feature extraction and classification of images. The classified image output of DBN is utilized by Polyp Detector. Residual network and feature extractor components of Polyp Detector helps polyp inspector in pixel wise learning. Two stage polyp network (PLPNet) is a R-CNN architecture with two stage advantage. The first stage is the extension of R-CNN to detect the polyp lesion area through a location box also called Polyp Inspector. Second Stage performs polyp segmentation. Polyp Inspector transfers the learned semantics to the polyp segmentation stage. It helps to enhance the ability to detect polyp with improved accuracy and guide the learning process. Skip schemes enrich the feature scale. Publicly available CVC-Clinical DB and CVC Colon DB datasets are used for experiment purposes to achieve a better prediction capability for clinical practices.

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          Most cited references25

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          3D-GLCM CNN: A 3-dimensional gray-level co-occurrence matrix based CNN model for polyp classification via CT colonography

          Accurately classifying colorectal polyps, or differentiating malignant from benign ones, has a significant clinical impact on early detection and identifying optimal treatment of colorectal cancer. Convolution neural network (CNN) has shown great potential in recognizing different objects (e.g. human faces) from multiple slice (or color) images, a task similar to the polyp differentiation, given a large learning database. This study explores the potential of CNN learning from multiple slice (or feature) images to differentiate malignant from benign polyps from a relatively small database with pathological ground truth, including 32 malignant and 31 benign polyps represented by volumetric computed tomographic (CT) images. The feature image in this investigation is the gray-level co-occurrence matrix (GLCM). For each volumetric polyp, there are 13 GLCMs, computed from each of the 13 directions through the polyp volume. For comparison purpose, the CNN learning is also applied to the multi-slice CT images of the volumetric polyps. The comparison study is further extended to include Random Forest (RF) classification of the Haralick texture features (derived from the GLCMs). From the relatively small database, this study achieved scores of 0.91/0.93 (two-fold/leave-one-out evaluations) AUC (area under curve of the receiver operating characteristics) by using the CNN on the GLCMs, while the RF reached 0.84/0.86 AUC on the Haralick features and the CNN rendered 0.79/0.80 AUC on the multiple-slice CT images. The presented CNN learning from the GLCMs can relieve the challenge associated with relatively small database, improve the classification performance over the CNN on the raw CT images and the RF on the Haralick features, and have the potential to perform the clinical task of differentiating malignant from benign polyps with pathological ground truth.
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            Deep learning can predict lymph node status directly from histology in colorectal cancer.

            Lymph node status is a prognostic marker and strongly influences therapeutic decisions in colorectal cancer (CRC).
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              Cervical Cancer Diagnosis Using Very Deep Networks Over Different Activation Functions

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                Author and article information

                Journal
                EAI Endorsed Transactions on Pervasive Health and Technology
                EAI Endorsed Trans Perv Health Tech
                European Alliance for Innovation n.o.
                2411-7145
                May 25 2023
                September 25 2023
                : 9
                Article
                10.4108/eetpht.9.3964
                af277594-aa3e-4216-80ba-f381534685d0
                © 2023

                https://creativecommons.org/licenses/by-nc-sa/4.0

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