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      Emotion reactivity and regulation in late-life generalized anxiety disorder: functional connectivity at baseline and post-treatment.

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          Abstract

          Generalized anxiety disorder (GAD) is one of the most prevalent mental disorders in the elderly, but its functional neuroanatomy is not well understood. Given the role of emotion dysregulation in GAD, we sought to describe the neural bases of emotion regulation in late-life GAD by analyzing the functional connectivity (FC) in the Salience Network and the Executive Control Network during worry induction and worry reappraisal.

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          Author and article information

          Journal
          Am J Geriatr Psychiatry
          The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
          1545-7214
          1064-7481
          Feb 2015
          : 23
          : 2
          Affiliations
          [1 ] Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: Andreescuc@upmc.edu.
          [2 ] Department of Psychology, University of Pittsburgh, Pittsburgh, PA.
          [3 ] Department of Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA; Department of Biostatistics, University of Pittsburgh School of Medicine, Pittsburgh, PA.
          [4 ] Department of Psychology, Stanford University, Stanford, CA.
          [5 ] Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
          [6 ] Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA.
          Article
          S1064-7481(14)00144-4 NIHMS599169
          10.1016/j.jagp.2014.05.003
          4234701
          24996397
          a3655c70-bad4-478b-be60-125f255a0047
          Copyright © 2015 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.
          History

          Functional connectivity,emotion regulation,late-life generalized anxiety disorder

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