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      US Adult Illicit Cannabis Use, Cannabis Use Disorder, and Medical Marijuana Laws : 1991-1992 to 2012-2013

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          Abstract

          This analysis presents data on medical marijuana laws, cannabis use, and cannabis use disorders from 3 US national surveys conducted approximately 10 years apart.

          Key Points

          Question

          Are US state medical marijuana laws one of the underlying factors for increases in risk for adult cannabis use and cannabis use disorders seen since the early 1990s?

          Findings

          In this analysis using US national survey data collected in 1991-1992, 2001-2002, and 2012-2013 from 118 497 participants, the risk for cannabis use and cannabis use disorders increased at a significantly greater rate in states that passed medical marijuana laws than in states that did not.

          Meaning

          Possible adverse consequences of illicit cannabis use due to more permissive state cannabis laws should receive consideration by voters, legislators, and policy and health care professionals, with appropriate health care planning as such laws change.

          Abstract

          Importance

          Over the last 25 years, illicit cannabis use and cannabis use disorders have increased among US adults, and 28 states have passed medical marijuana laws (MML). Little is known about MML and adult illicit cannabis use or cannabis use disorders considered over time.

          Objective

          To present national data on state MML and degree of change in the prevalence of cannabis use and disorders.

          Design, Participants, and Setting

          Differences in the degree of change between those living in MML states and other states were examined using 3 cross-sectional US adult surveys: the National Longitudinal Alcohol Epidemiologic Survey (NLAES; 1991-1992), the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; 2001-2002), and the National Epidemiologic Survey on Alcohol and Related Conditions–III (NESARC-III; 2012-2013). Early-MML states passed MML between NLAES and NESARC (“earlier period”). Late-MML states passed MML between NESARC and NESARC-III (“later period”).

          Main Outcomes and Measures

          Past-year illicit cannabis use and DSM- IV cannabis use disorder.

          Results

          Overall, from 1991-1992 to 2012-2013, illicit cannabis use increased significantly more in states that passed MML than in other states (1.4–percentage point more; SE, 0.5; P = .004), as did cannabis use disorders (0.7–percentage point more; SE, 0.3; P = .03). In the earlier period, illicit cannabis use and disorders decreased similarly in non-MML states and in California (where prevalence was much higher to start with). In contrast, in remaining early-MML states, the prevalence of use and disorders increased. Remaining early-MML and non-MML states differed significantly for use (by 2.5 percentage points; SE, 0.9; P = .004) and disorder (1.1 percentage points; SE, 0.5; P = .02). In the later period, illicit use increased by the following percentage points: never-MML states, 3.5 (SE, 0.5); California, 5.3 (SE, 1.0); Colorado, 7.0 (SE, 1.6); other early-MML states, 2.6 (SE, 0.9); and late-MML states, 5.1 (SE, 0.8). Compared with never-MML states, increases in use were significantly greater in late-MML states (1.6–percentage point more; SE, 0.6; P = .01), California (1.8–percentage point more; SE, 0.9; P = .04), and Colorado (3.5–percentage point more; SE, 1.5; P = .03). Increases in cannabis use disorder, which was less prevalent, were smaller but followed similar patterns descriptively, with change greater than never-MML states in California (1.0–percentage point more; SE, 0.5; P = .06) and Colorado (1.6–percentage point more; SE, 0.8; P = .04).

          Conclusions and Relevance

          Medical marijuana laws appear to have contributed to increased prevalence of illicit cannabis use and cannabis use disorders. State-specific policy changes may also have played a role. While medical marijuana may help some, cannabis-related health consequences associated with changes in state marijuana laws should receive consideration by health care professionals and the public.

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          Author and article information

          Journal
          JAMA Psychiatry
          JAMA Psychiatry
          JAMA Psychiatry
          JAMA Psychiatry
          American Medical Association
          2168-622X
          2168-6238
          26 April 2017
          7 June 2017
          June 2017
          7 June 2018
          : 74
          : 6
          : 579-610
          Affiliations
          [1 ]Department of Psychiatry, Columbia University Medical Center, New York, New York
          [2 ]New York State Psychiatric Institute, New York
          [3 ]Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York
          [4 ]Department of Emergency Medicine, University of California, Davis, Sacramento
          [5 ]School of Public Health, Boston University, Boston, Massachusetts
          [6 ]Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York
          Author notes
          Article Information
          Corresponding Author: Deborah S. Hasin, PhD, Department of Psychiatry, Columbia University Medical Center, 1051 Riverside Dr, Unit 123, New York, NY 10032 ( deborah.hasin@ 123456gmail.com ).
          Accepted for Publication: March 1, 2017.
          Published Online: April 26, 2017. doi:10.1001/jamapsychiatry.2017.0724
          Author Contributions: Mr Sarvet and Ms Stohl had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
          Study concept and design: Hasin, Sarvet, Galea, Wall.
          Acquisition, analysis, or interpretation of data: All authors.
          Drafting of the manuscript: Hasin, Sarvet, Stohl, Wall.
          Critical revision of the manuscript for important intellectual content: Hasin, Sarvet, Cerdá, Keyes, Galea, Wall.
          Statistical analysis: Sarvet, Stohl.
          Obtained funding: Hasin.
          Administrative, technical, or material support: Hasin, Cerdá, Keyes, Wall.
          Supervision: Hasin, Sarvet, Galea.
          Conflict of Interest Disclosures: None reported.
          Funding/Support: The design, conduct, data collection, and management of the 3 surveys analyzed in this article, the National Longitudinal Alcohol Epidemiologic Survey (NLAES), National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), and National Epidemiologic Survey on Alcohol and Related Conditions–III (NESARC-III), were sponsored by the National Institute on Alcohol Abuse and Alcoholism and funded in part by the Intramural Research Program of the National Institutes of Health, with additional support from the National Institute on Drug Abuse. Additionally, Dr Hasin is supported by grant R01DA034244 and Dr Cerdá by grants K01DA030449 and R01DA040924-01A1 from the National Institute on Drug Abuse, Dr Keyes by grant K01AA021511 from the National Institute on Alcohol Abuse and Alcoholism, and Drs Hasin and Wall from the New York State Psychiatric Institute.
          Role of the Funder/Sponsor: The funders had no role in the analysis and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
          Additional Contributions: We acknowledge the generosity of William Kerr, PhD (Director of the Alcohol Research Center) (funded by P50AA005595 from the National Institute on Alcohol Abuse and Alcoholism), for providing us with the prevalences of cannabis use in 1984 and 1990 from the National Alcohol Surveys 7 and 8.
          Article
          PMC5539836 PMC5539836 5539836 yoi170024
          10.1001/jamapsychiatry.2017.0724
          5539836
          28445557
          82d218cb-ffe5-485b-9621-61691cd330d5
          Copyright 2017 American Medical Association. All Rights Reserved.
          History
          : 4 November 2016
          : 27 February 2017
          : 1 March 2017
          Funding
          Funded by: National Institute on Alcohol Abuse and Alcoholism
          Funded by: Intramural Research Program of the National Institutes of Health
          Funded by: National Institute on Drug Abuse
          Funded by: National Institute on Drug Abuse
          Funded by: National Institute on Alcohol Abuse and Alcoholism
          Funded by: New York State Psychiatric Institute
          Categories
          Research
          Research
          Original Investigation
          Featured
          Online First

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