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      Physical Activity and Multimorbidity Among Community-Dwelling Older Adults: A Systematic Review With Meta-Analysis

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          Abstract

          Objective

          This study evaluated the relationship between physical activity (PA) and multimorbidity in community-dwelling older adults.

          Data Source

          A systematic review and meta-analysis in the following databases: Pubmed, Lilacs, Scielo, Web of Science, Scopus, and AgeLine.

          Study inclusion and Exclusion Criteria

          It included observational studies investigating the association between physical activity and multimorbidity, with older adults, published until May 2021. Studies with institutionalized individuals or that assessed specific diseases were excluded.

          Data Extraction

          Two reviewers independently extracted the studies based on previous inclusion and exclusion criteria, started by selecting titles, followed by abstracts and full-text reading.

          Data Synthesis

          Meta-analysis results were reported as Odds Ratio (OR) with a 95% confidence interval using R language. The Newcastle Ottawa scale was used to assess the quality of the studies.

          Results

          Fifteen studies were included in the systematic review, from which 12 reported an inverse association between physical activity and multimorbidity. In the meta-analysis, from over 77 000 older adults, there was an inverse association between physical activity and multimorbidity [OR: .81; 95% CI: .73-.89]. We found significant results only for men in the analysis by sex.

          Conclusions

          Low levels of physical activity were associated with a higher risk of multimorbidity in older adults. It is expected that public policies will be conducted aimed at the practice of physical activity among older adults.

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          Most cited references53

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          Measuring inconsistency in meta-analyses.

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            Meta-analysis of Observational Studies in EpidemiologyA Proposal for Reporting

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              Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases.

              This review provides the reader with the up-to-date evidence-based basis for prescribing exercise as medicine in the treatment of 26 different diseases: psychiatric diseases (depression, anxiety, stress, schizophrenia); neurological diseases (dementia, Parkinson's disease, multiple sclerosis); metabolic diseases (obesity, hyperlipidemia, metabolic syndrome, polycystic ovarian syndrome, type 2 diabetes, type 1 diabetes); cardiovascular diseases (hypertension, coronary heart disease, heart failure, cerebral apoplexy, and claudication intermittent); pulmonary diseases (chronic obstructive pulmonary disease, asthma, cystic fibrosis); musculo-skeletal disorders (osteoarthritis, osteoporosis, back pain, rheumatoid arthritis); and cancer. The effect of exercise therapy on disease pathogenesis and symptoms are given and the possible mechanisms of action are discussed. We have interpreted the scientific literature and for each disease, we provide the reader with our best advice regarding the optimal type and dose for prescription of exercise.
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                Author and article information

                Contributors
                (View ORCID Profile)
                (View ORCID Profile)
                Journal
                American Journal of Health Promotion
                Am J Health Promot
                SAGE Publications
                0890-1171
                2168-6602
                November 2022
                May 27 2022
                November 2022
                : 36
                : 8
                : 1371-1385
                Affiliations
                [1 ]Postgraduate Program in Nutrition and Food, Faculty of Nutrition, Federal University of Pelotas, Pelotas, Brazil
                [2 ]Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil
                [3 ]Postgraduate Program in Nursing, Federal University of Pelotas, Pelotas, Brazil
                [4 ]Postgraduate Program in Physical Education, Federal University of Pelotas, Pelotas, Brazil
                Article
                10.1177/08901171221104458
                35621359
                7c892eca-d5c2-4ee4-834b-013c6a94b4d0
                © 2022

                http://journals.sagepub.com/page/policies/text-and-data-mining-license

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