Association between birth weight and refractive error in adulthood: a Mendelian randomisation study.

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Abstract

Pathological myopia is one of the leading causes of blindness globally. Lower birth weight (BW) within the normal range has been reported to increase the risk of myopia, although findings conflict. We sought to estimate the causal effect of BW on refractive error using Mendelian randomisation (MR), under the assumption of a linear relationship.

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Journal

Journal ID (iso-abbrev): Br J Ophthalmol

Title: The British journal of ophthalmology

Publisher: BMJ

ISSN (Electronic): 1468-2079

ISSN (Print): 0007-1161

Publication date (Electronic): February 2020

Volume: 104

Issue: 2

Affiliations

[1 ] School of Optometry & Vision Sciences, Cardiff University, Cardiff, UK.

[2 ] Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

[3 ] School of Optometry & Vision Sciences, Cardiff University, Cardiff, UK GuggenheimJ1@cardiff.ac.uk.

Article

Publisher Item ID: bjophthalmol-2018-313640

DOI: 10.1136/bjophthalmol-2018-313640

PubMed ID: 31097437

SO-VID: 79ddbba8-960a-40ed-b621-429c30e3f28e

History

Keywords: birth weight,refractive error,Mendelian randomisation,UK Biobank

Data availability:

Keywords: birth weight, refractive error, Mendelian randomisation, UK Biobank

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