The Religious Orders Study and Rush Memory and Aging Project are both ongoing longitudinal clinical-pathologic cohort studies of aging and Alzheimer’s disease (AD).
To summarize progress over the past five years and its implications for understanding neurodegenerative diseases.
Participants in both studies are older adults who enroll without dementia and agree to detailed longitudinal clinical evaluations and organ donation. The last review summarized findings through the end of 2011. Here we summarize progress and study findings over the past five years, and discuss new directions for how these studies can inform on aging and AD in the future.