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      Electrospinning of natural polymers for the production of nanofibres for wound healing applications

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      Materials Science and Engineering: C
      Elsevier BV

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          Alginate: properties and biomedical applications.

          Alginate is a biomaterial that has found numerous applications in biomedical science and engineering due to its favorable properties, including biocompatibility and ease of gelation. Alginate hydrogels have been particularly attractive in wound healing, drug delivery, and tissue engineering applications to date, as these gels retain structural similarity to the extracellular matrices in tissues and can be manipulated to play several critical roles. This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.
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            The extracellular matrix at a glance.

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              Electrospinning: a fascinating fiber fabrication technique.

              With the emergence of nanotechnology, researchers become more interested in studying the unique properties of nanoscale materials. Electrospinning, an electrostatic fiber fabrication technique has evinced more interest and attention in recent years due to its versatility and potential for applications in diverse fields. The notable applications include in tissue engineering, biosensors, filtration, wound dressings, drug delivery, and enzyme immobilization. The nanoscale fibers are generated by the application of strong electric field on polymer solution or melt. The non-wovens nanofibrous mats produced by this technique mimics extracellular matrix components much closely as compared to the conventional techniques. The sub-micron range spun fibers produced by this process, offer various advantages like high surface area to volume ratio, tunable porosity and the ability to manipulate nanofiber composition in order to get desired properties and function. Over the years, more than 200 polymers have been electrospun for various applications and the number is still increasing gradually with time. With these in perspectives, we aim to present in this review, an overview of the electrospinning technique with its promising advantages and potential applications. We have discussed the electrospinning theory, spinnable polymers, parameters (solution and processing), which significantly affect the fiber morphology, solvent properties and melt electrospinning (alternative to solution electrospinning). Finally, we have focused on varied applications of electrospun fibers in different fields and concluded with the future prospects of this efficient technology. (c) 2010 Elsevier Inc. All rights reserved.
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                Author and article information

                Journal
                Materials Science and Engineering: C
                Materials Science and Engineering: C
                Elsevier BV
                09284931
                September 2020
                September 2020
                : 114
                : 110994
                Article
                10.1016/j.msec.2020.110994
                32993991
                6b7fc3c6-6c0a-4826-996b-63ab40a86f8e
                © 2020

                https://www.elsevier.com/tdm/userlicense/1.0/

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