The deficiencies in using large databases to assess the risk of future development of inflammatory bowel disease

Previous studies of an association between physical activity and inflammatory bowel disease have yielded conflicting results.

The primary purpose of this study was to evaluate the validity of an interviewer-administered, 24-h physical activity recall (PAR) compared with that of the SenseWear Armband (SWA) for estimation of energy expenditure (EE) and moderate-to-vigorous physical activity (MVPA) in a representative sample of adults. A secondary goal was to compare measurement errors for various demographic subgroups (gender, age, and weight status). A sample of 1347 adults (20-71 yr, 786 females) wore an SWA for a single day and then completed a PAR, recalling the previous day's physical activity. The participants each performed two trials on two randomly selected days across a 2-yr time span. The EE and MVPA values for each participant were averaged across the 2 d. Group-level and individual-level agreement were evaluated using 95% equivalence testing and mean absolute percent error, respectively. Results were further examined for subgroups by gender, age, and body mass index. The PAR yielded equivalent estimates of EE (compared with those in the SWA) for almost all demographic subgroups, but none of the comparisons for MVPA were equivalent. Smaller mean absolute percent error values were observed for EE (ranges from 10.3% to 15.0%) than those for MVPA (ranges from 68.6% to 269.5%) across all comparisons. The PAR yielded underestimates of MVPA for younger, less obese people but overestimates for older, more obese people. For EE measurement, the PAR demonstrated good agreement relative to the SWA. However, the use of PAR may result in biased estimates of MVPA both at the group and individual level in adults.

Delays in diagnosing pediatric inflammatory bowel disease (IBD) are common, but the extent of this delay remains unclear due to variations in reported time-periods between studies. The objectives of this systematic review were to examine the extent of diagnostic delay in pediatric IBD and examine any association between specific characteristics and length of diagnostic delay.