- Record: found
- Abstract: found
- Article: found
The Reactome pathway knowledgebase
David Croft ,
Antonio Fabregat Mundo ,
Robin Haw ,
Marija Milacic ,
Joel Weiser ,
Guanming Wu ,
Michael Caudy ,
Phani Garapati ,
Marc Gillespie ,
Maulik R. Kamdar ,
Bijay Jassal ,
Steven Jupe ,
Lisa Matthews ,
Bruce May ,
Stanislav Palatnik ,
Karen Rothfels ,
Veronica Shamovsky ,
Heeyeon Song ,
Mark Williams ,
Ewan Birney ,
Henning Hermjakob ,
Lincoln Stein ,
Peter D'Eustachio
December 28 2013
November 15 2013
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Reactome (http://www.reactome.org) is a manually curated open-source open-data resource
of human pathways and reactions. The current version 46 describes 7088 human proteins
(34% of the predicted human proteome), participating in 6744 reactions based on data
extracted from 15 107 research publications with PubMed links. The Reactome Web site
and analysis tool set have been completely redesigned to increase speed, flexibility
and user friendliness. The data model has been extended to support annotation of disease
processes due to infectious agents and to mutation.