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      Three case reports of acute paroxysmal excitement associated with alprazolam treatment.

      The American Journal of Psychiatry
      Acute Disease, Adult, Akathisia, Drug-Induced, Alprazolam, Anti-Anxiety Agents, adverse effects, Anxiety Disorders, drug therapy, Benzodiazepines, Bipolar Disorder, chemically induced, Female, Humans, Male, Panic

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          Abstract

          Three patients receiving alprazolam developed, within days after beginning treatment, acute excitatory states with features more suggestive of mania than of disinhibition syndrome. The authors suggest a neurochemical link between mania and disinhibitory states.

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