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      The magnetic field strength and the force distance dependency of the magnetically controlled growing rods used for early onset scoliosis

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          Abstract

          Magnetically controlled growing rods (MCGR’s) have revolutionized the treatment of early-onset scoliosis (EOS) because painless lengthenings can be done in the outpatient clinic without anesthesia. Untreated EOS leads to respiratory insufficiency and reduced life expectancy. However, MCGR’s have inherent complications like non-functioning of the lengthening mechanism. We quantify an important failure mechanism and give advice on how to avoid this complication. The magnetic field strength was measured on new/explanted rods at different distances between the external remote controller and the MCGR and likewise in patients before/after distractions. The magnetic field strength of the internal actuator decayed fast with increasing distances and plateaued at 25–30 mm approximating zero. Two new and 12 explanted MCGRs was used for the lab measurements of the elicited force using a forcemeter. At a distance of 25 mm, the force was reduced to approximately 40% (ca. 100 N) compared to zero distance (ca. 250 N), most so for explanted rods. This is used to point out the importance of minimizing the implantation depth to ensure proper functionality of the rod lengthening in clinical use for EOS patients. A distance of 25 mm from skin to MCGR should be considered a relative contraindication to clinical use in EOS patients.

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          Long-term follow-up of patients with untreated scoliosis. A study of mortality, causes of death, and symptoms.

          The mortality and causes of death in 115 patients (80 women), born 1902-1937, with untreated scoliosis were compared to the expected according to official Swedish statistics. Subgrouping for cause and onset of scoliosis was done. Fifty-five patients had died; 21 of respiratory failure and 17 of cardiovascular diseases. The mortality was significantly (P less than 0.001) increased. The increased risk was apparent at 40-50 years of age. The mortality was significantly increased in infantile (P less than 0.001) and juvenile (P less than 0.01) scoliosis but not in adolescent scoliosis. The mortality was also increased in post-polio scoliosis, scoliosis combined with rickets and scoliosis of unknown etiology indicating an increased mortality in idiopathic scoliosis. Among the surviving patients anti-hypertensive treatment was frequent (23 of 50).
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            Magnetically controlled growing rods for severe spinal curvature in young children: a prospective case series.

            Scoliosis in skeletally immature children is often treated by implantation of a rod to straighten the spine. Rods can be distracted (lengthened) as the spine grows, but patients need many invasive operations under general anaesthesia. Such operations are costly and associated with negative psychosocial outcomes. We assessed the effectiveness and safety of a new magnetically controlled growing rod (MCGR) for non-invasive outpatient distractions. We implanted the MCGR in five patients, two of whom have now reached 24 months' follow-up. Each patient underwent monthly outpatient distractions. We used radiography to measure the magnitude of the spinal curvature, rod distraction length, and spinal length. We assessed clinical outcome by measuring the degree of pain, function, mental health, satisfaction with treatment, and procedure-related complications. In the two patients with 24 months' follow-up, the mean degree of scoliosis, measured by Cobb angle, was 67° (SD 10°) before implantation and 29° (4°) at 24 months. Length of the instrumented segment of the spine increased by a mean of 1·9 mm (0·4 mm) with each distraction. Mean predicted versus actual rod distraction lengths were 2·3 mm (1·2 mm) versus 1·4 mm (0·7 mm) for patient 1, and 2·0 mm (0·2 mm) and 2·1 mm (0·7 mm) versus 1·9 mm (0·6 mm) and 1·7 mm (0·8 mm) for patient 2's right and left rods, respectively. Throughout follow-up, both patients had no pain, had good functional outcome, and were satisfied with the procedure. No MCGR-related complications were noted. The MCGR procedure can be safely and effectively used in outpatient settings, and minimises surgical scarring and psychological distress, improves quality of life, and is more cost-effective than is the traditional growing rod procedure. The technique could be used for non-invasive correction of abnormalities in other disorders. Ellipse Technologies. Copyright © 2012 Elsevier Ltd. All rights reserved.
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              Systematic review of the complications associated with magnetically controlled growing rods for the treatment of early onset scoliosis.

              To analyse the complication profile of magnetically controlled growing rods (MCGRs) in early onset scoliosis (EOS).
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                Author and article information

                Contributors
                spe@rn.dk
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                21 February 2023
                21 February 2023
                2023
                : 13
                : 3045
                Affiliations
                [1 ]GRID grid.5117.2, ISNI 0000 0001 0742 471X, Physics Group, Department of Materials and Production, , Aalborg University, ; Skjernvej 4A, 9220 Aalborg Ø, Denmark
                [2 ]GRID grid.27530.33, ISNI 0000 0004 0646 7349, Department of Orthopedic Surgery, , Aalborg University Hospital, ; Hobrovej 18-22, 9000 Aalborg C, Denmark
                [3 ]Department of Clinical Medicine, Faculty of Medicine, Søndre Skovvej 15, 9000 Aalborg C, Denmark
                [4 ]GRID grid.27530.33, ISNI 0000 0004 0646 7349, Aalborg University Hospital, ; Hobrovej 18-22, 9000 Aalborg C, Denmark
                Article
                30232
                10.1038/s41598-023-30232-8
                9944223
                36810891
                4535e36e-1a65-4be4-a97c-590567ee0695
                © The Author(s) 2023

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 8 January 2023
                : 20 February 2023
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                © The Author(s) 2023

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                medical research,physics
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                medical research, physics

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