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Differential effectiveness of placebo treatments: a systematic review of migraine prophylaxis.
Karin Meissner
1 ,
Margrit Fässler ,
Gerta Rücker ,
Jos Kleijnen ,
Asbjorn Hróbjartsson ,
Antonius Schneider ,
Gerd Antes ,
Klaus Linde
Nov 25 2013
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
When analyzing results of randomized clinical trials, the treatment with the greatest specific effect compared with its placebo control is considered to be the most effective one. Although systematic variations of improvements in placebo control groups would have important implications for the interpretation of placebo-controlled trials, the knowledge base on the subject is weak.