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      Radiological Imaging of Gastro-Entero-Pancreatic Neuroendocrine Tumors. The Review of Current Literature Emphasizing the Diagnostic Value of Chosen Imaging Methods

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          Abstract

          Despite development of radiologic imaging, detection and follow-up of neuroendocrine neoplasms (NENs) still pose a diagnostic challenge, due to the heterogeneity of NEN, their relatively long-term growth, and small size of primary tumor. A set of information obtained by using different radiological imaging tools simplifies a choice of the most appropriate treatment method. Moreover, radiological imaging plays an important role in the assessment of metastatic lesions, especially in the liver, as well as, tumor response to treatment. This article reviews the current, broadly in use imaging modalities which are applied to the diagnosis of GEP-NETs, (the most common type of NENs) and put emphasis on the strengths and limitations of each modality.

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          Most cited references61

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          Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States.

          The incidence and prevalence of neuroendocrine tumors (NETs) are thought to be rising, but updated epidemiologic data are lacking.
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            ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatic Neuroendocrine Tumors

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              Gastroenteropancreatic neuroendocrine neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

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                Author and article information

                Contributors
                Journal
                Front Oncol
                Front Oncol
                Front. Oncol.
                Frontiers in Oncology
                Frontiers Media S.A.
                2234-943X
                15 June 2021
                2021
                : 11
                : 670233
                Affiliations
                [1] 1 Department of Radiology, Centre of Postgraduate Medical Education , Warsaw, Poland
                [2] 2 Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw , Warsaw, Poland
                [3] 3 Department of Nuclear Medicine, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw , Warsaw, Poland
                [4] 4 University of Humanities and Economics , Lodz, Poland
                Author notes

                Edited by: Georgios S. Limouris, National and Kapodistrian University of Athens, Greece

                Reviewed by: Roberta Modica, University of Naples Federico II, Italy; Sikandar Shaikh, Shadan Hospital and Institute of Medical Sciences, India

                *Correspondence: Bartosz Mruk, bartosz.mruk@ 123456hotmail.com ; Gabriela Półtorak-Szymczak, gabriela.poltorak@ 123456gmail.com

                This article was submitted to Cancer Imaging and Image-directed Interventions, a section of the journal Frontiers in Oncology

                Article
                10.3389/fonc.2021.670233
                8239281
                34211845
                2aeb2fa2-041e-420a-9ff6-ea02b2dae6df
                Copyright © 2021 Półtorak-Szymczak, Budlewski, Furmanek, Wierzba, Sklinda, Walecki and Mruk

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 20 February 2021
                : 14 April 2021
                Page count
                Figures: 0, Tables: 1, Equations: 0, References: 63, Pages: 7, Words: 3173
                Categories
                Oncology
                Review

                Oncology & Radiotherapy
                gastro-entero-pancreatic neuroendocrine tumor,magnetic resonance imaging,computed tomography,ultrasonography,radiology,neuroendocrine tumor

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