Estimating the rate of evolution of the rate of molecular evolution.

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Abstract

A simple model for the evolution of the rate of molecular evolution is presented. With a Bayesian approach, this model can serve as the basis for estimating dates of important evolutionary events even in the absence of the assumption of constant rates among evolutionary lineages. The method can be used in conjunction with any of the widely used models for nucleotide substitution or amino acid replacement. It is illustrated by analyzing a data set of rbcL protein sequences.

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Journal

Journal ID (iso-abbrev): Mol Biol Evol

Title: Molecular biology and evolution

Publisher: Oxford University Press (OUP)

ISSN: 0737-4038

ISSN (Print): 0737-4038

Publication date (Electronic): Dec 1998

Volume: 15

Issue: 12

Affiliations

[1 ] Statistics Department, North Carolina State University, Raleigh 27695-8203, USA. thorne@statgen.ncsu.edu

Article

DOI: 10.1093/oxfordjournals.molbev.a025892

PubMed ID: 9866200

SO-VID: 1a9f4b37-a306-4f7c-9a3d-05ba863a8aa8

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