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      Bilateral osteoporotic bone marrow defects of the mandible: a case report

      case-report

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          Abstract

          Osteoporotic bone marrow defect of the jaws has been reported as a poorly demarcated radiolucency that affect mainly posterior mandible of middle-aged woman. The incidence of this condition is not exactly established and its pathogenesis remains unknown. An additional unusual case of osteoporotic bone marrow defects occurring bilaterally in the mandibular edentulous regions of a 32-year-old white woman is presented reinforcing its diagnostic criteria and histopathological findings.

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          Focal osteoporotic marrow defect: report of 100 new cases with ultrasonography scans.

          Focal osteoporotic marrow defect (FOMD) may be the earliest detectable form of the ischemic marrow disorders. The exact cause is unknown, but three theories have been proposed in the literature. A fourth is presented in this paper. In this study, 100 biopsies were examined histologically and were diagnosed as FOMD, based upon consistent histological characteristics. Until recently, the only diagnostic criteria were radiographic evaluation and incisional biopsy. In February 2002, a through-transmission alveolar ultrasonic test (Cavitat 4000, Cavitat Medical Technologies, Inc., Aurora, CO) was approved by the US Food and Drug Administration and by Health Canada for detection of low bone density and bone desiccation, both features of FOMD and chronic ischemic bone disease. Within this article, the diagnostic criteria and pathological findings of FOMD will be presented. The three current theories concerning its etiology will be briefly presented and a fourth theory will be proposed.
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            Focal osteoporotic bone marrow defects of the jaws.

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              Focal osteoporotic bone marrow defects of the jaws.

              Twenty focal osteoporotic bone marrow defects of the jaws were analyzed clinically, histologically, and radiographically; the findings were compared with those from all known published cases. Radiologic and clinical criteria that are useful for making a definitive diagnosis are discussed, and five radiologic categories are proposed.
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                Author and article information

                Journal
                Head Face Med
                Head Face Med
                Head & Face Medicine
                BioMed Central
                1746-160X
                2012
                8 August 2012
                : 8
                : 22
                Affiliations
                [1 ]Department of Stomatology, Area of Pathology, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9–75, Bauru, 17012-901, SP, Brazil
                [2 ]Private Practice, Rua Almirante Barroso, 1433, Ji-Paraná, 76900-079, RO, Brazil
                [3 ]Bauru School of Dentistry, Department of Stomatology, Area of Pathology, Alameda Octávio Pinheiro Brisolla, 9–75 CEP 17012–901, Bauru, São Paulo, Brazil
                Article
                1746-160X-8-22
                10.1186/1746-160X-8-22
                3489784
                22873712
                15275eb5-0876-4095-bd4a-4e51e8ec90ad
                Copyright ©2012 Bravo-Calderón et al.; licensee BioMed Central Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 12 June 2012
                : 30 July 2012
                Categories
                Case Report

                Orthopedics
                bone marrow pathology,radiography,mandible
                Orthopedics
                bone marrow pathology, radiography, mandible

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