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Cancer Drug Design and Discovery
edited-book
Publication date
(Print):
2014
Publisher:
Elsevier
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UCL: UN SDG 03 Good Health and Well-Being
Author and book information
Book
ISBN (Print):
9780123965219
Publication date (Print):
2014
DOI:
10.1016/C2011-0-07765-7
SO-VID:
0c02993c-8347-42c4-a229-3ffa1a62a153
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Book chapters
pp. iii
Front Matter
pp. iv
Copyright
pp. ix
Introduction
pp. xi
Cancer Drug Design and Discovery
pp. xv
Editor Biography
pp. xvii
Contributors
pp. 1
Color Plates
pp. 3
Modern Cancer Drug Discovery
pp. 55
Pharmacogenomics and Personalized Medicines in Cancer Treatment
pp. 91
Natural Product Chemistry and Cancer Drug Discovery
pp. 121
Structural Biology and Anticancer Drug Design
pp. 145
Temozolomide
pp. 165
Temozolomide
pp. 177
A New Generation of Cell-Targeted Drugs for Cancer Treatment
pp. 193
Inhibition of DNA Repair as a Therapeutic Target
pp. 239
Exploiting Cancer Dependence on Molecular Chaperones
pp. 275
Inhibitors of Tumor Angiogenesis
pp. 319
The Renaissance of CYP17 Inhibitors for the Treatment of Prostate Cancer
pp. 357
Apoptosis in Cancer
pp. 391
Targeting the MDM2–p53 Protein–Protein Interaction
pp. 427
Targeting Altered Metabolism—Emerging Cancer Therapeutic Strategies
pp. 449
Inhibitors of the Phosphatidylinositol 3-Kinase Pathway
pp. 479
Antibody–Drug Conjugates Delivering DNA Cytotoxics
pp. 491
Inhibition of Telomerase
pp. 529
Targeting B-RAF
pp. 567
Failure Modes in Anticancer Drug Discovery and Development
pp. 583
Anticancer Drug Registration and Regulation
pp. 609
Glossary
pp. 613
Index
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