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Handbook of Toxicology of Chemical Warfare Agents
Ricin
edited_book
Author(s):
Ramesh C. Gupta
,
Harry Salem
Publication date
(Print):
2020
Publisher:
Elsevier
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Author and book information
Book Chapter
Publication date (Print):
2020
Pages
: 413-426
DOI:
10.1016/B978-0-12-819090-6.00028-3
SO-VID:
98e63193-d69e-4d75-bd7c-56844dc449ff
License:
https://www.elsevier.com/tdm/userlicense/1.0/
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Book chapters
pp. i
Title page
pp. iv
Copyright
pp. v
Dedication
pp. vii
Contents
pp. xxvii
List of contributors
pp. xxxiii
Introduction
pp. 3
History of toxicology: from killers to healers
pp. 17
Historical perspective of chemical warfare agents
pp. 27
Global impact of chemical warfare agents used before and after 1945
pp. 37
Sarin attacks in Japan: acute and delayed health effects in survivors
pp. 55
Early and delayed effects of sulfur mustard in Iranian veterans after the Iraq–Iran conflict
pp. 67
Epidemiology of chemical warfare agents
pp. 79
Chemical weapons of mass destruction and terrorism: a threat analysis
pp. 97
Organophosphate nerve agents
pp. 127
Russian VX
pp. 143
Novichoks
pp. 149
Blister agents
pp. 171
Riot control agents
pp. 197
Phosgene oxime
pp. 203
Psychotomimetic agent BZ (3-quinuclidinyl benzilate)
pp. 215
Fluoroacetate
pp. 239
Strychnine
pp. 249
Superwarfarins
pp. 267
PCBs, dioxins, and furans: human exposure and health effects
pp. 279
Polycyclic aromatic hydrocarbons: implications for developmental, molecular, and behavioral neurotoxicity
pp. 299
Thallium
pp. 303
Arsenicals: toxicity, their use as chemical warfare agents, and possible remedial measures
pp. 321
Chlorine
pp. 341
Phosgene
pp. 353
Carbon monoxide: can’t see, can’t smell, body looks red but they are dead
pp. 373
Acute cyanide toxicity and its treatment: the body is dead and may be red but does not stay red for long
pp. 389
Methyl isocyanate: the Bhopal gas
pp. 403
Other toxic chemicals as potential chemical warfare agents
pp. 413
Ricin
pp. 427
Botulinum toxin
pp. 455
Onchidal and fasciculins
pp. 467
Cyanobacterial (blue-green algae) toxins
pp. 481
Chemical warfare agents and the nervous system
pp. 499
Behavioral toxicity of nerve agents
pp. 515
The respiratory toxicity of chemical warfare agents
pp. 545
The cardiovascular system as a target of chemical warfare agents
pp. 567
Ocular toxicity of chemical warfare agents
pp. 589
Skeletal muscle
pp. 613
Dermal toxicity of sulfur mustard
pp. 641
Reproductive toxicity and endocrine disruption of potential chemical warfare agents
pp. 659
Liver toxicity of chemical warfare agents
pp. 673
Renal system
pp. 685
Impact of chemical warfare agents on the immune system
pp. 707
Health effects of nuclear weapons and releases of radioactive materials
pp. 745
Clinical and cellular aspects of traumatic brain injury
pp. 767
Neurological effects and mechanisms of blast overpressure injury
pp. 779
Genomics and proteomics in brain complexity in relation to chemically induced posttraumatic stress disorder
pp. 795
Excitotoxicity, oxidative stress, and neuronal injury
pp. 811
Blood–brain barrier damage and dysfunction by chemical toxicity
pp. 829
The effects of organophosphates in the early stages of human skeletal muscle regeneration
pp. 843
Experimental modeling for delayed effects of organophosphates
pp. 853
Alternative animal toxicity testing of chemical warfare agents
pp. 875
Toxicokinetic aspects of nerve agents and vesicants
pp. 921
Toxicokinetics and toxicodynamics of DFP
pp. 945
Physiologically based pharmacokinetic modeling of chemical warfare agents
pp. 953
Biotransformation of warfare nerve agents
pp. 969
Laboratory analysis of chemical warfare agents, adducts, and metabolites in biomedical samples
pp. 983
On-site detection of chemical warfare agents
pp. 1005
Neuropathy target esterase as a biomarker and biosensor of delayed neuropathic agents
pp. 1027
The cross-linking action of organophosphorus poisons; Implications for chronic neurotoxicity
pp. 1035
Monitoring of blood cholinesterase activity in workers exposed to nerve agents
pp. 1049
Potential agents that can cause contamination of animal feedingstuff and terror
pp. 1061
Chemical warfare agents and risks to animal health
pp. 1077
Threats to wildlife by chemical and warfare agents
pp. 1091
Pharmacological prophylaxis against nerve agent poisoning: experimental studies and practical implications
pp. 1103
Prophylactic and therapeutic measures in nerve agents poisonings
pp. 1121
Physiologically based pharmacokinetic/pharmacodynamic modeling of countermeasures to nerve agents
pp. 1135
Research on medical countermeasures for chemical attacks on civilians
pp. 1145
Pyridinium oximes in the treatment of poisoning with organophosphorus compounds
pp. 1161
Novel cholinesterase reactivators
pp. 1179
Paraoxonase (PON1), detoxification of nerve agents, and modulation of their toxicity
pp. 1191
The role of carboxylesterases in therapeutic interventions of nerve agent poisoning
pp. 1199
Catalytic bioscavengers: the second generation of bioscavenger-based medical countermeasures
pp. 1233
Rapid decontamination of chemical warfare agents from skin
pp. 1249
Index
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