A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy.

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Abstract

Translational research suggests that D-cycloserine (DCS), a partial N-methyl-D-aspartate (NMDA) receptor agonist, might facilitate fear extinction and exposure therapy by either enhancing NMDA receptor function during extinction or by reducing NMDA receptor function during fear memory consolidation. This article provides a quantitative review of DCS-augmented fear extinction and exposure therapy literature.

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Journal

Journal ID (iso-abbrev): Biol Psychiatry

Title: Biological psychiatry

Publisher: Elsevier BV

ISSN (Electronic): 1873-2402

ISSN (Print): 0006-3223

Publication date (Electronic): Jun 15 2008

Volume: 63

Issue: 12

Affiliations

[1 ] Institute of Living, New Haven, CT 06106, USA.

Article

Publisher Item ID: S0006-3223(08)00106-6

DOI: 10.1016/j.biopsych.2008.01.012

PubMed ID: 18313643

SO-VID: 679c8bac-2afc-4ce0-adcf-77933f29680f

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