Similar amino acid sequences: chance or common ancestry?

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Abstract

The systemic comparison of every newly determined amino acid sequence with all other known sequences may allow a complete reconstruction of the evolutionary events leading to contemporary proteins. But sometimes the surviving similarities are so vague that even computer-based sequence comparisons procedures are unable to validate relationships. In other cases similar sequences may appear in totally alien proteins as a result of mere chance or, occasionally, by the convergent evolution of sequences with special properties.

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Journal

Journal ID (iso-abbrev): Science

Title: Science (New York, N.Y.)

Publisher: American Association for the Advancement of Science (AAAS)

ISSN: 0036-8075

ISSN (Print): 0036-8075

Publication date (Electronic): Oct 09 1981

Volume: 214

Issue: 4517

Article

DOI: 10.1126/science.7280687

PubMed ID: 7280687

SO-VID: b5890d3f-9667-4359-86f7-fa9615e869c0

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