Individual sensitivity to genotoxic effects of nickel and antimutagenic activity of ascorbic acid.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Cytotoxicity of nickel compounds was studied by stimulating the repair synthesis of DNA and counting lymphocyte micronuclei in workers of smelting shop of copper-nickel sulfide processing plant. Nickel content in the organism was evaluated by its concentrations in hair. Therapy with ascorbic acid (1 g/day for 1 month) led to a significant decrease in the number of micronuclei. The number of micronuclei before and after ascorbic acid treatment varied within a wide range in different individuals.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Bull Exp Biol Med

Title: Bulletin of experimental biology and medicine

Publisher: Springer Science and Business Media LLC

ISSN: 0007-4888

ISSN (Print): 0007-4888

Publication date (Electronic): Apr 2001

Volume: 131

Issue: 4

Affiliations

[1 ] Group of Medical Ecological Studies, Institute of Industrial Ecology Problems of the North, Karelian Research Center, Russian Academy of Sciences, Apatity.

Article

DOI: 10.1023/a:1017912521543

PubMed ID: 11550028

SO-VID: b56d1318-8f0f-4272-9833-493d3ff7a9d4

History

Data availability:

Comments

Comment on this article

scite_

0

Smart Citations

0

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.