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      The wide pharmacological versatility of semicarbazones, thiosemicarba-zones and their metal complexes.

      Mini Reviews in Medicinal Chemistry
      Anti-Infective Agents, pharmacology, Anticonvulsants, Antineoplastic Agents, Organometallic Compounds, Radiopharmaceuticals, diagnostic use, Semicarbazones, agonists, Thiosemicarbazones

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          Abstract

          The more significant bioactivities of a variety of semicarbazones (anti-protozoa, anticonvulsant) and thiosemicarbazones (antibacterial, antifungal, antitumoral, antiviral) and their metal complexes are reviewed together with proposed mechanisms of action and structure-activity relationships. Clinical or potential pharmacological applications of these versatile compounds are discussed.

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